刘夕强 外科学(普外)

博士、副主任医师、硕士生导师

减重与代谢外科主任
       

研究方向:肝胆胰外科、微创外科、肿瘤免疫
       

个人履历:博士毕业于上海交通大学,从事外科工作20年,作为访问学者于美国匹兹堡大学学习3个月,熟练掌握肝胆外科常见及各类疑难疾病的诊疗。对门静脉高压及肝胆胰肿瘤的发病机制有较深入的研究,相关研究成果以第一/通讯作者发表于Journal of Experimental & Clinical Cancer Research,BBA - Molecular Basis of Disease,The American Journal of Pathology等高水平论文期刊,并被各类高水平论文期刊引用近百次,担任Journal of Hematology & Oncology,CANCER LETTERS, LIVER TRANSPLANTATION等多篇高水平论文期刊的审稿专家。承担/参与多项国家及省级课题的研究。

       

学术任职:广东省肝癌与肝转移瘤专业委员会委员

       

科研论文:

       1. Wu XB, Feng X, Chang QM, Zhang CW, Wang ZF, Liu J, Hu ZQ, LiuJZ, WuWD, ZhangZP,Liu XQ. Cross-talk among AFAP1-AS1, ACVR1 and microRNA-384 regulates the stemness of pancreatic cancer cells and tumorigenicity in nude mice. J Exp Clin Cancer Res 2019;38:107.       

       2. Pei YF, Liu J, Cheng J, Wu WD, LiuXQ. Silencing of LAMC2 Reverses Epithelial-Mesenchymal Transition and Inhibits Angiogenesis in Cholangiocarcinoma via Inactivation of the Epidermal Growth Factor Receptor Signaling Pathway. Am J Pathol2019;189:1637-1653.

       3. Pei YF, Xu XN, Wang ZF, Wang FW, Wu WD, Geng JF, Liu XQ. Methyl-CpG Binding Domain Protein Inhibits the Malignant Characteristic of Lung Adenocarcinoma through the Epigenetic Modulation of 10 to 11 Translocation 1 and miR-200s. Am J Pathol 2019;189:1065-1076.

       4.Pei YF, Yin XM, Liu XQ. TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway. BiochimBiophys Acta 2018;1864:197-207.

       5.Pei YF, Lei Y, Liu XQ. Mir-29a promotes cell proliferation and EMT in breast cancer by targeting ten eleven translocation 1. BiochimBiophys Acta 2016.

       6.Liu XQ, Hu ZQ, Pei YF, Tao R. Clinical operational tolerance in liver transplantation: state-of-the-art perspective and future prospects. Hepatobiliary Pancreat Dis Int 2013;12:12-33.

       7.Wang Y, Liu W, Liu X, Sheng M, Pei Y, Lei R, Zhang S, et al. Role of liver in modulating the release of inflammatory cytokines involved in lung and multiple organ dysfunction in severe acute pancreatitis. Cell Biochem Biophys 2015;71:765-776.

      8.Qinyun Chen, Xiqiang Liu, Ran Tao. Survey of the self-management and self-efficacy status in patients after orthotopic liver transplantation. 5th Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA), Singapore, 18–21 March 2015.(Accepted conference papers)

      9.Xiqiang Liu, Timothy R. Billiar, Ran Tao. Hepatic inflammasome activation plays a dominant role in the hepatotoxic effect of bile acids. 5th Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA), Singapore, 18–21 March 2015. (Accepted conference papers)

      10.Xiqiang Liu, Ran Tao. The vasopressin analogue terlipressin protects the liver from oxidative stress induced apoptosis via the wnt-beta-catenin-sgk1-foxo3 pathway. 5th Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA), Singapore, 18–21 March 2015. (Accepted conference papers)

      11.Xiqiang Liu, Ran Tao. Inflammasome Activation in Hepatocytes and Kupffer Cells Orchestrates the Hepatotoxic Effect of Bile Acids and Can BePotential Target in the Management of Cholestatic Liver Injury. American Transplant Congress (ATC), Pennsylvania Convention Center, May 2-6, 2015. (Accepted conference papers)

       12.Xiqiang Liu, Ran Tao.Engagement of the Vasopressin Receptor On Hepatocytes Protects Liver from Ischemia-Reperfusion Injury Via the WNT-β-Catenin-SGK1-FOXO Pathway. American Transplant Congress (ATC), Pennsylvania Convention Center, May 2-6, 2015. (Accepted conference papers)

主持科研项目:1、长链非编码RNA MIAT 通过 mTOR 途径调控肝癌侵袭和转移的机制研究,浙江省基础公益研究计划项目 2、中药血必净通过清利湿热对胆道感染治疗作用的研究,浙江省中医药科技计划项目(主持,在研)。 3、TEX19表达对预后影响的临床研究,浙江省医药卫生科研项目

 

       

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